Washington University in St. Louis has contracted with the following investigators and institutions to assist in the conduct of the project research:
Alzheimer’s Disease Cooperative Study (ADCS): Paul Aisen, MD—coordination of clinical and neuropsychological evaluations and monitoring of the acquisition of imaging studies and collection of biological fluids.
Mayo Clinic, Rochester, MN: Clifford Jack, MD, PhD—MRI site training and standardization.
University of Michigan: Robert Koeppe, PhD—PET site training and standardization.
University of Pittsburgh: Chester Mathis, PhD—[11C]PIB site training and standardization.
San Francisco Veteran’s Administration Medical Center: Michael Weiner, MD— Principal Investigator Alzheimer’s Disease Neuroimaging Initiative (ADNI).
A steering committee composed of DIAN's principal investigators, associate directors, executive director, core leaders, performance site leaders, prinicpal investigators from ADNI and the ADCS, a bioethicist, autosomal dominant Alzheimer's disease family representatives, representatives of the Food and Drug Administration, and appropriate staff from the National Institute of Aging will govern the research.
Washington University (DIAN Coordinating Center; Performance Site)
John C. Morris, Director and Principal Investigator
David M. Holtzman, Associate Director
Alison M. Goate, Associate Director & Genetics Core Leader
Virginia Buckles, Executive Director
Randall Bateman, Clinical Core Leader
Chengjie Xiong, Biostatistics Core Leader
Nigel J. Cairns, Neuropathology Core Leader
Anne M. Fagan, Biomarker Core Leader
Tammie Benzinger, Imaging Core Leader
Dan Marcus, Informatics Core Leader
Other Performance Site Leaders
Reisa Sperling (Site PI), Massachusetts General Hospital/Brigham and Women's Hospital
Stephen Salloway (Site PI), Butler Hospital/Brown University
Richard Mayeux (Site PI), Columbia University
Bernardino Ghetti (Site PI), Indiana University
John Ringman (Site PI), University of California, Los Angeles
Martin Rossor (Site PI), University College, London/Institute of Neurology
Eric McDade (Site PI), University of Pittsburgh
Neill Graff-Radford (Site PI), Mayo Clinic Jacksonville
Peter Schofield (Australian Consortium PI),Neuroscience Research Australia, Sydney
Ralph Martins, Edith Cowan University, Perth
Colin Masters, University of Melbourne
German DIAN Sites
Mathias Jucker (Site PI), University of Tübingen
Adrian Danek (Site PI), University of Munich
Other Steering Committee Members
Paul Aisen, Alzheimer's Disease Cooperative Study
Michael W. Weiner, Alzheimer's Disease Neuroimaging Initiative
Kimberly Quaid, Indiana University Center for Biothics
Neil Buckholtz and John K. Hsiao, National Institute on Aging
Two members of families with dominantly inherited Alzheimer's disease
Resource Allocation Review Committee
A Resource Allocation Review Committee (RARC) will review requests for the use of biospecimens and recommend approval or disapproval to the Steering Committee.
David M. Holtzman (Chair), Washington University
Alison M. Goate, Washington University
Nigel J. Cairns, Washington University
Anne Fagan, Washington University
John K. Hsiao, National Institute on Aging
Gerard Schellenberg, University of Pennsylvania
John Q. Trojanowski, University of Pennsylvania
External Advisory Committee
Members of the External Advisory Committee (EAC) will review DIAN annually to evaluate progress, assess the effectiveness of communication among the grant components, and ensure that the conduct of the sites is of the highest possible quality. Current EAC members are:
Thomas Bird (Chair), University of Washington
Thomas Montine, University of Washington
Eric Reiman, Banner Health, Phoenix
Roger Rosenberg, University of Texas/Southwestern, Dallas
Peter St. George-Hyslop, University of Toronto